Glutathione Reductase anticorps

N° du produit ABIN5708412

L’anticorps Lapin Polyclonal anti-Glutathione Reductase a été validé pour WB, ELISA, ICC, IHC (p) et FACS. Il convient pour détecter Glutathione Reductase dans des échantillons de Humain, Rat et Souris. Il y a 1 publication disponible.

Aperçu rapide pour Glutathione Reductase anticorps (ABIN5708412)

Antigène: Glutathione Reductase (GSR)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutathione Reductase est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Glutathione Reductase anticorps

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids K256-R522 was used as the immunogen for the Glutathione Reductase antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Glutathione Reductase antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ICC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Glutathione Reductase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Références pour anticorps anti-Glutathione Reductase (ABIN5708412)

Kronstein-Wiedemann, Stadtmüller, Traikov, Georgi, Teichert, Yosef, Wallenborn, Karl, Schütze, Wagner, El-Armouche, Tonn: "SARS-CoV-2 Infects Red Blood Cell Progenitors and Dysregulates Hemoglobin and Iron Metabolism." dans: Stem cell reviews and reports, (2022) (PubMed).

Détails sur Glutathione Reductase

Antigène: Glutathione Reductase (GSR)

Autre désignation: Glutathione Reductase / GSR

Sujet: Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis